To achieve a complete understanding of the involvement of lipids in physiological processes and to develop compounds of therapeutic interest, it is vital not only to identify and characterize existing and novel lipids but also to quantify changes in their metabolites, and develop biochemical pathways and interaction network maps involving lipids. Lipids and their metabolites play an important role in the regulation and control of cellular function and disease. The LMSD is publicly available at Author Webpage Search results, in addition to structure and annotations, also include relevant links to external databases. The structure-based search, in conjunction with optional data fields, provides the capability to perform a substructure search or exact match for the structure drawn by the user. The text-based search implementation supports data retrieval by any combination of these data fields: LIPID MAPS ID, systematic or common name, mass, formula, category, main class, and subclass data fields. In addition to a classification-based retrieval of lipids, users can search LMSD using either text-based or structure-based search options. All the lipid structures in LMSD are drawn in a consistent fashion. Structures of lipids in the database come from four sources: (i) LIPID MAPS Consortium's core laboratories and partners (ii) lipids identified by LIPID MAPS experiments (iii) computationally generated structures for appropriate lipid classes (iv) biologically relevant lipids manually curated from LIPID BANK, LIPIDAT and other public sources. The LIPID MAPS Structure Database (LMSD) is a relational database encompassing structures and annotations of biologically relevant lipids.
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